In the growing field of neuro-oncology, the past few years have witnessed rapid advances in tumor classification, treatment modalities, and the role of neurologists and neuro-oncologists. Neuro-Oncology for the Clinical Neurologist is a first-of-its-kind resource that focuses on patient-clinical scenarios relevant to the practicing neurologist-bringing you up to date with everything from basic principles and neuro-oncology imaging consults to neurologic complications of radiation, systemic, and immune-based therapies, and much more.
Table of Contents:
Dedication
Roy Strowd
Acknowledgments
Roy Strowd
Foreword
Roy Strowd
Section 1: Basic principles of neuro-oncology
1. Fundamentals of neuropathology: introduction to neuropathology and molecular diagnostics
Sonika Dahiya and Shakti Ramkissoon
2. Surgical considerations for brain and spine tumors
Michelle Marie Williams, Stephen B. Tatter, and Adrian W. Laxton
3. Introduction to radiation therapy
Emily Schapira, Marc R. Bussière, and Helen A. Shih
4. Evidence-based approaches to chemotherapy for gliomas
Alessia Pellerino, Federica Franchino, Roberta Rudà, and Riccardo Soffietti
Section 2: Neuro-oncology imaging consults
5. Evaluation of a dural-based lesion
Carol Parks Geer and David Wayne Robinson
6. Evaluation of a supratentorial parenchymal brain lesion
Albert E. Kim and Elizabeth R. Gerstner
7. Evaluation of an infratentorial lesion
David E. Kram, Jacob J. Henderson, and Daniel E. Couture
8. Imaging of spinal lesions
Teddy Earl Kim, Carl Nechtman, and Wesley Hsu
9. Evaluation of peripheral nerve lesions
K. Ina Ly and Justin T. Jordan
Section 3: Approach to patients with primary and secondary CNS tumors
10. Approach to the meningioma patient
Jennifer Lynn Franke, Christina Jackson, and Michael Lim
11. Approach to the low-grade glioma patient
Carlos G. Romo, Ananyaa Sivakumar, and Matthias Holdhoff
12. Approach to the high-grade glioma patient
David Olayinka Kamson and Stuart Grossman
13. Approach to the CNS lymphoma patient
Ahmad Nader Kassem and David M. Peereboom
14. Approach to a brain metastasis patient
Michael H. Soike and Michael D. Chan
15. Approach to the leptomeningeal metastases patient
Jigisha Thakkar and Priya Kumthekar
Section 4: Inherited tumor syndromes in neuro-oncology
16. Approach to patients with the neoplasms associated with neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis
Jaishri O. Blakeley, Shannon Langmead, and Peter de Blank
17. Approach to the patient with tuberous sclerosis
Mary T. Silvia and Roy Strowd
18. Approach to Von Hippel Lindau, Cowden disease, and other inherited conditions
Sapna Pathak, Thuy M. Vu, and Roy Strowd
Section 5: Neurologic complications of cancer
19. Neurologic complications of cancer
Andrea Wasilewski and Nimish Mohile
20. Paraneoplastic neurologic disorder syndromes
Luisa A. Diaz-Arias and John C. Probasco
21. Perineural spread of cancer
Kutluay Uluc, Laszlo Szidonya, Joao Prola Netto, and Prakash Ambady
22. Cancer-associated plexopathy
Mary Jane Lim-Fat, Patrick Y. Wen, and Ugonma N. Chukwueke
23. Cancer complications in patients with hematologic malignancies
Cristina Valencia-Sanchez, Molly Knox, and Maciej M. Mrugala
Section 6: Neurologic complications of radiation therapy
24. Approach to the patient with radiation necrosis
Jiayi Huang, Lauren E. Henke and Jian Campian
25. Neurologic complications of radiation
Christina Kehl Cramer and Tiffany L. Cummings
26. Uncommon radiation-induced neurologic syndromes
Shivani Sud, Courtney Michelle Vaughn, and Colette Shen
Section 7: Neurologic complications of systemic therapy
27. Approach to the patient with a delayed post-treatment CNS neurotoxicity
Amy Pruitt
28. Approach to chemotherapy-induced peripheral neuropathy
Taylor Brooks and Roy Strowd
Section 8: Neurologic complications of immune-based cancer therapies
29. Neurologic complications of immune checkpoint inhibitors
Sarah E. Mancone and Roy Strowd
30. Neurologic complications associated with CAR T-cell therapy
Stephen J. Bagley
Summary of clinical pearls
Roy Strowd
